CK-MB

Labkit

Immunoinhibition | Kinetic UV .

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Creatine kinase (CK) is a cytosolic carrier protein for high-energy phosphates.CK-MB is an isoenzyme of CK that is most abundant in the heart. However, CK-MB also constitutes 1% to 3% of the CK in skeletal muscle and is present in a small fraction in other organs, such as the small bowel, uterus, prostate, and diaphragm. Among the first biomarkers applied in clinical routine for the detection of myocardial necrosis were creatine kinase myocardial band (CK-MB) and myoglobin. Due to a rather slow dynamic change, CK-MB is of secondary importance for acute decision-making. However, an increase of CK-MB remains an important biomarker for patients with diagnosed AMI.

 

Furthermore, current ESC guidelines recommend CK-MB as the preferred biomarker for patients who present early after prior AMI,  as the rapid decline of CK-MB to the reference interval by 48 to 72 hours allows for the discrimination of early re-infarction when symptoms recur between 72 hours and 2 weeks after the index acute MI, when troponin may still be elevated.

Product Features:

  • Immuno-inhibition, kinetic rate.
  • Ready to use reagent.
  • Programmable on most of the fully automated analyzers as well as semiautomatic analyzers.
  • Very good correlation with other commercial reagents.
  • AMR = 1 ~ 600 iU/L.

Product Code

Description

Pack Size

Standard/Control

 

 

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